Article

Myeloperoxidase

2003-11-21

Abstract excerpt

Myeloperoxidase (MPO) is an haemoprotein that metabolizes tobacco smoke procarcinogens such as benzo(a)pyrene and aromatic amines into highly reactive intermediates. A polymorphism in the MPO promoter (−463G>A), resulting in lower expression, was previously associated with a decrease in lung cancer risk. In this study, the MPO gene was analysed for new polymorphisms by denaturing high-performance liquid chromatogr...

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Literature Corpus work: 152f03e2-4402-542f-87f1-1d4f9509c284
DOI: 10.1097/00008571-200312000-00004

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