Article

Integrative genomics analysis implicates decreased <i>FGD6</i> expression underlying risk of intracranial aneurysm rupture

2022-03-14

Abstract excerpt

<h4>Background</h4> The genetic determinants and mechanisms underlying intracranial aneurysm rupture (rIA) are largely unknown. Given the ∼50% mortality rate of rIA, approaches to identify patients at high-risk will inform screening, diagnostic, and preventative measures. <h4>Objective</h4> Our goal was to identify and characterize the genetic basis of rIA. <h4>Methods</h4> We perform a genome-wide association stu...

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Literature Corpus work: 937715d8-f72f-5874-8f8f-e96d89d72384
DOI: 10.1101/2022.03.12.22272299

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