Article
Genetic risk factors for intracranial aneurysms: a meta-analysis in more than 116,000 individuals.
Neurology - 4 Jun 2013
Alg Varinder S, Sofat Reecha, Houlden Henry, Werring David J
Abstract excerpt
OBJECTIVE: There is an urgent need to identify risk factors for sporadic intracranial aneurysm (IA) development and rupture. A genetic component has long been recognized, but firm conclusions have been elusive given the generally small sample sizes and lack of replication. Genome-wide association studies have overcome some limitations, but the number of robust genetic risk factors for IA remains uncertain....
Topics
- Chromosomes, Human, Pair 4
- Chromosomes, Human, Pair 8
- Chromosomes, Human, Pair 9
- Genome-Wide Association Study
- Humans
- Intracranial Aneurysm
- Polymorphism, Single Nucleotide
- Risk Factors