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Article

Identifying novel risk genes in intracranial aneurysm by integrating human proteomes and genetics.

Brain : a journal of neurology - 1 Aug 2024

Wu Congyan, Liu Hanchen, Zuo Qiao, Jiang Aimin, Wang Chuanchuan, Lv Nan, Lin Ruyue, Wang Yonghui, Zong Kang, Wei Yanpeng, Huang Qinghai, Li Qiang, Yang Pengfei, Zhao Rui, Liu Jianmin

Abstract excerpt

Genome-wide association studies (GWAS) have become increasingly popular for detecting numerous loci associated with intracranial aneurysm (IA), but how these loci function remains unclear. In this study, we employed an integrative analytical pipeline to efficiently transform genetic associations and identify novel genes for IA. Using multidimensional high-throughput data, we integrated proteome-wide association...

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PMID: 39084678
DOI: 10.1093/brain/awae111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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