Article

Melanocortin-1 receptor (<i>MC1R</i>) genotypes do not correlate with size in two cohorts of medium-to-giant congenital melanocytic nevi

2020-04-14

Abstract excerpt

<h4>ABSTRACT</h4> Congenital melanocytic nevi (CMN) are cutaneous malformations whose prevalence is inversely correlated with projected adult size. CMN are caused by somatic mutations, but epidemiological studies suggest that germline genetic factors may influence CMN development. In CMN patients from the U.K., genetic variants in the MC1R gene, such as p.V92M and loss-of-function variants, have been previously as...

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Literature Corpus work: 931c218f-7275-5000-973b-0326d84fc138
DOI: 10.1101/2020.04.10.20055301

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