Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Melanocortin 1 receptor function: shifting gears from determining skin and nevus phenotype to fetal growth.

The Journal of investigative dermatology - 1 Aug 2012

Gruis Nelleke A, van Doorn Remco

Abstract excerpt

Variants in the MC1R gene influence skin pigmentation and thereby modulate risk of melanoma and basal and squamous cell carcinoma. In this issue, Kinsler et al. report an association between the MC1R genotype and the development of congenital melanocytic nevi. Further, higher birth weight was observed in carriers of MC1R variants, suggesting a role for the melanocortin network in fetal growth.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression Regulation, Developmental
Share to Genotype
Share to Receptor, Melanocortin, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22797298
DOI: 10.1038/jid.2012.216

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Melanocortin 1 receptor function: shifting gears from determining skin and nevus phenotype to fetal growth.PMID 22797298Read ↗

Germline melanocortin-1-receptor genotype is associated with severity of cutaneous phenotype in congenital melanocytic nevi: a role for MC1R in human fetal development.Semantic proximity Read ↗

Widespread dynamic and pleiotropic expression of the melanocortin-1-receptor (MC1R) system is conserved across chick, mouse and human embryonic developmentSemantic proximity Read ↗

Melanocortin 1 receptor variants: functional role and pigmentary associations.Semantic proximity Read ↗

Melanocortin 1 receptor (MC1R) polymorphisms' influence on size and dermoscopic features of nevi.Semantic proximity Read ↗

The Melanocortin-1 ReceptorSemantic proximity Read ↗

Melanocortin-1 receptor (<i>MC1R</i>) genotypes do not correlate with size in two cohorts of medium-to-giant congenital melanocytic neviSemantic proximity Read ↗

Melanocortin-1 receptor (MC1R): a review for dermatologists.Semantic proximity Read ↗

Variants of the melanocortin-1 receptor: do they matter clinically?Semantic proximity Read ↗

The melanocortin-1 receptor gene polymorphism and association with human skin cancer.Semantic proximity Read ↗

Melanocortin MC₁ receptor in human genetics and model systems.Semantic proximity Read ↗

Melanocortin 1 receptor variants, pigmentation, and skin cancer susceptibility.Semantic proximity Read ↗

Defining the quantitative contribution of the melanocortin 1 receptor (MC1R) to variation in pigmentary phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.