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Article

Population-based study of natural variation in the melanocortin-1 receptor gene and melanoma.

Cancer research - 15 Sept 2006

Kanetsky Peter A, Rebbeck Timothy R, Hummer Amanda J, Panossian Saarene, Armstrong Bruce K, Kricker Anne, Marrett Loraine D, Millikan Robert C, Gruber Stephen B, Culver Hoda Anton, Zanetti Roberto, Gallagher Richard P, Dwyer Terence, Busam Klaus, From Lynn, Mujumdar Urvi, Wilcox Homer, Begg Colin B, Berwick Marianne

Abstract excerpt

Natural variation in the coding region of the melanocortin-1 receptor (MC1R) gene is associated with constitutive pigmentation phenotypes and development of melanoma and nonmelanoma skin cancers. We investigated the effect of MC1R variants on melanoma using a large, international population-based study design with complete determination of all MC1R coding region variants. Direct sequencing was completed for 2,202...

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Identifiers

PMID: 16982779
DOI: 10.1158/0008-5472.CAN-06-1634

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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