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Article

Melanocortin-1 receptor (MC1R): a review for dermatologists.

Italian journal of dermatology and venereology - 1 Jun 2024

Guida Stefania, Puig Susana, DI Resta Chiara, Sallustio Fabio, Mangano Eleonora, Stabile Giorgio, Longo Caterina, Pellacani Giovanni, Guida Gabriella, Rongioletti Franco

Abstract excerpt

Melanocortin-1 receptor (MC1R) and its variants have a pivotal role in melanin synthesis. However, MC1R has been associated to non-pigmentary pathways related to DNA-repair activities and inflammation. The aim of this review is to provide an up-to-date overview about the role of MC1R in the skin. Specifically, after summarizing the current knowledge about MC1R structure and polymorphisms, we report data...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 38376504
DOI: 10.23736/S2784-8671.24.07839-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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