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Article

The role of MC1R gene variants and phenotypical features in predicting high nevus count.

Melanoma research - 1 Oct 2020

van der Poel Louise A J, Bergman Wilma, Gruis Nelleke A, Kukutsch Nicole A

Abstract excerpt

Variants in the Melanocortin 1 Receptor (MC1R) gene have been associated with an increased risk of melanoma, but the role in nevus count is unclear. We investigated if specific MC1R gene variants or the number of MC1R gene variants and phenotypical features were associated with nevus count. A total of 494 participants of the 'Leiden skin cancer study' were included and the MC1R gene coding sequence was analysed...

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Identifiers

PMID: 32732695
DOI: 10.1097/CMR.0000000000000687

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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