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Article

MC1R gene variants and non-melanoma skin cancer: a pooled-analysis from the M-SKIP project.

British journal of cancer - 14 Jul 2015

Tagliabue E, Fargnoli M C, Gandini S, Maisonneuve P, Liu F, Kayser M, Nijsten T, Han J, Kumar R, Gruis N A, Ferrucci L, Branicki W, Dwyer T, Blizzard L, Helsing P, Autier P, García-Borrón J C, Kanetsky P A, Landi M T, Little J, Newton-Bishop J, Sera F, Raimondi S

Abstract excerpt

BACKGROUND: The melanocortin-1-receptor (MC1R) gene regulates human pigmentation and is highly polymorphic in populations of European origins. The aims of this study were to evaluate the association between MC1R variants and the risk of non-melanoma skin cancer (NMSC), and to investigate whether risk estimates differed by phenotypic characteristics. METHODS: Data on 3527 NMSC cases and 9391 controls were gathered...

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Identifiers

PMID: 26103569
DOI: 10.1038/bjc.2015.231
PMCID: PMC4506395

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Source receipt: pubmed, retrieved 7 Sept 2026.

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