Article

Somatic development of Wilms tumour via normal kidneys in predisposed children

2024-08-06

Abstract excerpt

<h4>ABSTRACT</h4> Ten percent of children with cancer harbour a predisposition mutation. In children with the kidney cancer, Wilms tumour, the prevalence is as high as 30%. Certain predispositions are associated with defined histological and clinical features, suggesting differences in tumour genetic development. To investigate this, we assembled a cohort of 137 children with Wilms tumour, of whom 71 had a pathoge...

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Literature Corpus work: 92f66ec8-fa01-509d-a996-d13c454df8d6
DOI: 10.1101/2024.08.05.24310618

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