Article
Inherited cancer syndromes in children and young adults.
Journal of pediatric hematology/oncology - 1 Apr 2010
D'Orazio John A
Abstract excerpt
Geneticists estimate that 5% to 10% of all cancers diagnosed in the pediatric age range occur in children born with a genetic mutation that directly increases their lifetime risk for neoplasia. However, despite the fact that only a fraction of cancers in children occur as a result of an identified inherited predisposition, characterizing genetic mutations responsible for increased cancer risk in such syndromes...
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