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Article

Improving the diagnosis of renal tumours of young people through integrated molecular analysis.

Journal of cancer research and clinical oncology - 3 Apr 2026

Leiter Sarah M, Guobadia Aisosa O, Fleming Ben, Ajithkumar Thankamma V, Armitage James N, Burke G A Amos, Burns Charlotte M, Coleman Nicholas, Hatcher Helen, Horan Gail, Long Anna-May, McDonald Sarah, Mitchell Thomas J, Nicholson James C, Roberts Thomas, Stewart Grant D, Tadross John A, Tarpey Patrick S, Trayers Claire, Trotman Jamie, Watkins James A, Warren Anne Y, Vujanic Gordan M, Armstrong Ruth, Behjati Sam, Hook C Elizabeth, Murray Matthew J

Abstract excerpt

BACKGROUND: Renal tumours account for one in twenty paediatric cancers, with Wilms tumour (WT) the most common in young children and renal cell carcinoma (RCC) predominating in adolescents and young adults. Diagnostic work-up has traditionally focused on clinical features, radiology, and histology, with a limited role for molecular analysis. However, it is estimated that up to one-third of children with WT have...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41933220
DOI: 10.1007/s00432-026-06455-3
PMCID: PMC13049143

Genes

CCNY
ERC1
REST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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