Article
The pathological and molecular genetic landscape of the hereditary renal cancer predisposition syndromes.
Histopathology - 1 Jul 2022
Al-Obaidy Khaleel I, Alruwaii Zainab I, Williamson Sean R, Cheng Liang
Abstract excerpt
It is estimated that 5-8% of renal tumours are hereditary in nature, with many inherited as autosomal-dominant. These tumours carry a unique spectrum of pathological and molecular alterations, the knowledge of which has expanded in recent years. Due to this knowledge, many advances in the treatment of these tumours have been achieved. In this review, we summarize the current understanding of the genetic renal...
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