Article

Periostin <sup>+</sup> stromal cells guide lymphovascular invasion by cancer cells

2022-05-20

Abstract excerpt

Cancer cell dissemination to the sentinel lymph node associates with poor patient outcomes, particularly in breast cancers. How cancer cells egress the primary tumor upon interfacing with the lymphatic vasculature is complex and driven by dynamic interactions between cancer cells and stromal cells including cancer associated fibroblasts (CAFs). The matricellular protein periostin can distinguish CAF subtypes in br...

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Literature Corpus work: 92d583f4-a709-5323-984f-e38be883673f
DOI: 10.1101/2022.05.19.492742

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