Article

Spatiotemporal dynamics of tumor microenvironment remodeling

2025-07-18

Abstract excerpt

During tumorigenesis, interactions between tumor and stromal cells progressively remodel the tumor microenvironment (TME) towards pro-tumoral functions. Understanding early TME remodeling dynamics is therefore crucial for developing interceptive therapies. However, clinical samples typically provide isolated, late tumorigenesis snapshots. To overcome this limitation, we generated triple-negative breast cancer mice...

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Literature Corpus work: e24a361e-00af-579d-98cf-64f59ad04442
DOI: 10.1101/2025.07.15.662972

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