Article

Sensory neurons shape γδ T cell effector programs to control Psoriasiform Inflammation

2026-07-09

Abstract excerpt

Psoriasis is a chronic autoimmune skin disorder marked by IL-17 producing gamma delta T cell (γδT17) and pruritus, but immunoregulatory roles of itch-inducing neurons in this context remain unclear. This study addressed whether non-peptidergic (NP) afferents bearing the Mas-related G protein-coupled receptor D (MrgprD/NP1) and MrgprA3/NP2 subsets had differential effects on psoriasiform immunopathology. Data show...

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Literature Corpus work: 92d35468-43cc-5c05-b44b-45c995f1ec05
DOI: 10.64898/2026.07.03.736363

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