Article

Presynaptic inhibition of cutaneous afferents prevents self-generated itch

2019-10-16

Abstract excerpt

<h4>Summary</h4> Chronic itch represents an incapacitating burden on patients suffering a wide spectrum of diseases. Despite recent advances in our understanding of the cells and circuits implicated in the processing of itch information, chronic itch often presents itself without apparent cause. Here, we identify a spinal subpopulation of inhibitory neurons defined by the expression of Ptf1a involved in gating me...

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Literature Corpus work: e87599b3-5594-530a-a29b-6a0cd289189a
DOI: 10.1101/806976

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