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Article

The PLAUR signaling promotes chronic pruritus

21 May 2022

Abstract excerpt

Abstract Chronic itch is a complex sensation of the skin frequently associated with skin diseases, such as atopic dermatitis (AD) and psoriasis. Although Serpin E1 is implicated in chronic itch, its receptor and signaling pathways involved in itch are not known. In this study, the clinical relevance of a putative Serpin E1 receptor PLAUR to chronic itch, and the neuro‐cutaneous Serpin E1‐PLAUR signaling are...

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Identifiers

PMID: 35596683
DOI: 10.1096/fj.202200079r

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