Natriuretic peptides modulate monocyte-derived Langerhans cell differentiation and promote a migratory phenotype

Abstract excerpt

Introduction The interaction between the nervous and immune systems is crucial for maintaining homeostasis and can influence disease progression in inflammatory skin diseases, such as atopic dermatitis (AD). Sensory neurons in the skin can secrete neuropeptides that modulate immune cell activity, including Langerhans cells (LCs), one of the primary antigen-presenting cells in the epidermis. In our study we...

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