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Convergent evolution of epigenome recruited DNA repair across the Tree of Life

2024-10-18

Abstract excerpt

Mutations fuel evolution while also causing diseases like cancer. Epigenome-targeted DNA repair can help organisms protect important genomic regions from mutation. However, the adaptive value, mechanistic diversity, and evolution of epigenome-targeted DNA repair systems across the tree of life remain unresolved. Here, we investigated the evolution of histone reader domains fused to the DNA repair protein MSH6 (Mut...

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Literature Corpus work
92c99c32-0812-5895-91da-40544d929f14
DOI
10.1101/2024.10.15.618488
Open publication

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Convergent evolution of epigenome recruited DNA repair across the Tree of LifeDOI 10.1101/2024.10.15.618488
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