Article

Co-opted transposons help perpetuate conserved higher-order chromosomal structures

2018-12-05

Abstract excerpt

<h4>ABSTRACT</h4> Transposable elements (TEs) make up half of mammalian genomes and shape genome regulation by harboring binding sites for regulatory factors. These include architectural proteins—such as CTCF, RAD21 and SMC3—that are involved in tethering chromatin loops and marking domain boundaries. The 3D organization of the mammalian genome is intimately linked to its function and is remarkably conserved. How...

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Literature Corpus work: 3c2d98c7-3d2a-5321-923f-a71481100029
DOI: 10.1101/485342

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