Back to search

Article

African Americans and European Americans exhibit distinct gene expression patterns across tissues and tumors that are associated with immunologic and infectious functions and environmental exposures

2020-10-08

Abstract excerpt

<title>Abstract</title> <p>The COVID-19 pandemic has affected African American populations disproportionately with respect to prevalence, morbidity, and mortality. Because gene expression profiles represent combined genetic, socioenvironmental, and physiological effects, and could provide therapeutic biomarkers and environmental mitigation strategies, we undertook a large-scale assessment of differential gene exp...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
fd9429ef-6b41-58d6-ab15-6459084acd06
DOI
10.21203/rs.3.rs-88890/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
African Americans and European Americans exhibit distinct gene expression patterns across tissues and tumors that are associated with immunologic and infectious functions and environmental exposuresDOI 10.21203/rs.3.rs-88890/v1
African Americans and European Americans exhibit distinct gene expression patterns across tissues and tumors associated with immunologic functions and environmental exposuresSemantic proximity
Differential expression of COVID-19-related genes in European Americans and African AmericansSemantic proximity
<i>ACE2</i> and <i>TMPRSS2</i> expression by clinical, HLA, immune, and microbial correlates across 34 human cancers and matched normal tissues: implications for SARS-COV-2 COVID-19Semantic proximity
ACE2 and TMPRSS2 expression by clinical, HLA, immune, and microbial correlates across 34 human cancers and matched normal tissues: implications for SARS-CoV-2 COVID-19Semantic proximity
Multi-omic characterization of early-onset esophagogastric cancerSemantic proximity
Genetic and non-genetic factors affecting the expression of COVID-19 relevant genes in the large airway epitheliumSemantic proximity
Expression Level Analysis of ACE2 Receptor Gene in African-American and Non-African-American COVID-19 PatientsSemantic proximity
Integrated analyses of single-cell RNA-seq public data reveal the gene regulatory network landscape of respiratory epithelial and peripheral immune cells in COVID-19 patientsSemantic proximity
Ancestry-associated transcriptomic profiles of breast cancer in patients of African, Arab, and European ancestrySemantic proximity
The scRNA-seq expression profiling of the receptor ACE2 and the cellular protease TMPRSS2 reveals human organs susceptible to COVID-19 infectionSemantic proximity
Using genome and transcriptome data from African-ancestry female participants to identify putative breast cancer susceptibility genes.Semantic proximity
Extremes of age are associated with differences in the expression of selected pattern recognition receptor genes and ACE2, the receptor for SARS-CoV-2: implications for the epidemiology of COVID-19 diseaseSemantic proximity
Select a neighboring publication to make it the new centre.