Article
ADGR: Admixture-Informed Differential Gene Regulation.
Genes - 5 Jan 2023
Lee In-Hee, Kong Sek Won
Abstract excerpt
The regulatory elements in proximal and distal regions of genes are involved in the regulation of gene expression. Risk alleles in intronic and intergenic regions may alter gene expression by modifying the binding affinity and stability of diverse DNA-binding proteins implicated in gene expression regulation. By focusing on the local ancestral structure of coding and regulatory regions using the paired...
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