Article

Scalable Generation of Pseudo-Unipolar Sensory Neurons from Human Pluripotent Stem Cells

2022-03-27

Abstract excerpt

<h4>ABSTRACT</h4> Development of new non-addictive analgesics requires advanced strategies to differentiate human pluripotent stem cells (hPSCs) into relevant cell types amenable for translational research. Here, we developed a highly efficient and reproducible method that differentiates hPSCs into peptidergic and non-peptidergic nociceptors. By modulating specific cell signaling pathways, hPSCs were first conver...

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Literature Corpus work: 92a99d2f-29da-5453-89db-d31fcab8587e
DOI: 10.1101/2022.03.24.485622

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