Article

A Transcriptomic Comparison of the HD10.6 Human Sensory Neuron-Derived Cell Line with Primary and iPSC Sensory Neurons

2025-04-05

Abstract excerpt

<h4>ABSTRACT</h4> A key concern in early-stage analgesic discovery efforts is the extent to which mechanisms identified in rodents will translate to humans. To evaluate an alternative approach to the use of rodent dissociated DRG neurons for in vitro analyses of nociceptive signaling, we performed a transcriptomic analysis of the HD10.6 human dorsal root ganglion (DRG)-derived immortalized cell line. We conducted...

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Literature Corpus work: cf9f374a-4000-55b4-b29b-3665a9f44c4e
DOI: 10.1101/2025.04.03.643725

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