Article

Generation of human nociceptor-enriched sensory neurons for the study of pain-related dysfunctions

2022-02-20

Abstract excerpt

In vitro models of the peripheral nervous system would benefit from further refinements to better support studies on neuropathies. In particular, the assessment of pain-related signals is still difficult in human cell cultures. Here, we harnessed induced pluripotent stem cells (iPSCs) to generate peripheral sensory neurons enriched in nociceptors. The objective was to generate a culture system with signaling endpo...

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Literature Corpus work: ba0094a1-39ae-50e3-8196-ed3f57bdb920
DOI: 10.1101/2022.02.19.480828

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