Article

Human microphysiological model of dorsal root ganglion-spinal cord dorsal horn circuitry recapitulates opioid induced effects

2025-09-04

Abstract excerpt

Microphysiological systems (MPSs) are engineered, in vitro platforms which have been established as viable alternatives to animal models for pre-clinical research with unique advantages over conventional model systems. Many MPSs utilize 3-dimensional (3D) tissue constructs that enable biomimetic cell-cell interactions, allow for extended culture periods, and provide the time necessary for the emergence of physical...

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Literature Corpus work: ca4d5ca8-9888-51bc-9af8-1f8dab33017d
DOI: 10.1101/2025.08.31.673344

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