Article
Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells.
Scientific reports - 12 Jan 2018
Alshawaf Abdullah Jawad, Viventi Serena, Qiu Wanzhi, D'Abaco Giovanna, Nayagam Bryony, Erlichster Michael, Chana Gursharan, Everall Ian, Ivanusic Jason, Skafidas Efstratios, Dottori Mirella
Abstract excerpt
The dorsal root ganglia (DRG) consist of a multitude of sensory neuronal subtypes that function to relay sensory stimuli, including temperature, pressure, pain and position to the central nervous system. Our knowledge of DRG sensory neurons have been predominantly driven by animal studies and considerably less is known about the human DRG. Human embryonic stem cells (hESC) are valuable resource to help close this...
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