Article

A Multiplex Droplet Digital PCR Assay for Chromosome Copy Number Determination in <i>Candida albicans</i>

2026-02-10

Abstract excerpt

Chromosome copy number variation (CNV) is a major contributor to genome plasticity and adaptation in Candida albicans , a leading fungal pathogen of humans. Aneuploidy, defined as deviations from the normal diploid chromosome set, rapidly alters gene dosage, enabling tolerance to host-imposed and antifungal stress. Accurate detection and quantification of chromosomal copy number changes are thus essential to diss...

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Literature Corpus work: 926148d4-19b7-5abd-a545-077cb9b129e1
DOI: 10.64898/2026.02.09.704919

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