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Single Color Multiplexed ddPCR Copy Number Measurements and Single Nucleotide Variant Genotyping.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018

Wood-Bouwens Christina M, Ji Hanlee P

Abstract excerpt

Droplet digital PCR (ddPCR) allows for accurate quantification of genetic events such as copy number variation and single nucleotide variants. Probe-based assays represent the current "gold-standard" for detection and quantification of these genetic events. Here, we introduce a cost-effective single color ddPCR assay that allows for single genome resolution quantification of copy number and single nucleotide...

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PMID: 29717451
DOI: 10.1007/978-1-4939-7778-9_18

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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