Article

Potassium channel regulators are differentially expressed in hippocampi of Ts65Dn and Tc1 Down syndrome mouse models

2018-11-11

Abstract excerpt

<h4>Background:</h4> Down syndrome remains the main genetic cause of intellectual disability, with an incidence rate of about 1 in 700 live births. The Ts65Dn mouse strain, with an extra murine chromosome that includes genes from chromosomes 10, 16 and 17 of the mouse and the Tc1 strain with an extra human chromosome 21, are currently accepted as informative and well-studied models for Down Syndrome. Using whole...

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Literature Corpus work: 91f4711c-a2ce-56de-a2a7-370867ea3176
DOI: 10.1101/467522

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