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Respiratory tract <i>Moraxella catarrhalis</i> and <i>Klebsiella pneumoniae</i> can promote pathogenicity of myelin-reactive Th17 cells

2023-03-30

Abstract excerpt

The respiratory tract is home to a diverse microbial community whose influence on local and systemic immune responses is only beginning to be appreciated. The airways have been linked with trafficking of myelin-specific T cells in the pre-clinical stages of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis. Th17 cells are important pathogenic effectors in MS and EAE but are inn...

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Literature Corpus work
917efbbb-54ec-5e8a-87d6-cd8946341878
DOI
10.1101/2023.03.30.534905
Open publication

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