Article

Diverse <i>Streptococcus pneumoniae</i> strains drive a MAIT cell response through MR1-dependent and cytokine-driven pathways

2017-07-06

Abstract excerpt

Mucosal Associated Invariant T (MAIT) cells represent an innate T cell population of emerging significance. These abundant cells can recognize ligands generated by microbes utilizing the riboflavin synthesis pathway, presented via the major histocompatibility complex (MHC) class I-related molecule MR1 and binding of specific T cell receptors (TCR). They also possess an innate functional programme allowing microbia...

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Literature Corpus work: 0ac8085a-3a79-5db0-bb3f-7a815f033488
DOI: 10.1101/158204

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