Article

Cigarette smoke sets up a pro-inflammatory circuit in the lung that induces the hyper-activation of autoreactive T helper cells

2025-08-09

Abstract excerpt

Cigarette smoke (CS) exposure increases the risk of multiple sclerosis; however, the mechanisms are unclear. To investigate this, we exposed C57BL6/J mice to CS or ambient air (AA) for 8 weeks using a protocol modelling human chronic CS exposure and studied the impact of these exposures on the development of experimental autoimmune encephalomyelitis (EAE). We found that CS increased the incidence of neurological s...

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Literature Corpus work: 40d3dd30-f974-521e-bd7b-e3327bc38cc6
DOI: 10.1101/2025.08.06.668725

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