Article

Longitudinal dynamics of mutant huntingtin and neurofilament light in Huntington’s disease: the prospective HD-CSF study

2020-03-31

Abstract excerpt

The longitudinal dynamics of the most promising biofluid biomarker candidates for Huntington’s disease (HD) – mutant huntingtin (mHTT) and neurofilament light (NfL) – are incompletely defined, but could help understand the natural history of the disease and how these biomarkers might help in therapeutic development and the clinic. In an 80-participant cohort over 24 months, mHTT in cerebrospinal fluid (CSF), and N...

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Literature Corpus work: 9100fd50-07e4-5122-8a1a-3fe8cec3de5d
DOI: 10.1101/2020.03.31.20045260

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