Article

Validation of Serum Neurofilament Light Chain as a Biomarker of Parkinson’s Disease Progression

2019-09-11

Abstract excerpt

<h4>Objective</h4> To assess neurofilament light chain (NfL), as a biomarker for Parkinson’s disease (PD). <h4>Methods</h4> We quantified NfL in (1) longitudinal CSF samples from PD, other cognate/neurodegenerative disorders (OND), and healthy controls (HC); (2) a cross-sectional cohort with paired CSF and serum samples from participants with PD, OND, and HC, and (3) a large longitudinal validation cohort with s...

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Literature Corpus work: 591758a6-7f1d-5469-838d-28e0d699f37b
DOI: 10.1101/762237

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