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Article

Neurofilament Light Protein as a Potential Blood Biomarker for Huntington's Disease in Children

18 Apr 2022

Abstract excerpt

BACKGROUND: Juvenile-onset Huntington's disease (JOHD) is a rare and particularly devastating form of Huntington's disease (HD) for which clinical diagnosis is challenging and robust outcome measures are lacking. Neurofilament light protein (NfL) in plasma has emerged as a prognostic biomarker for adult-onset HD. METHODS: We performed a retrospective analysis of samples and data collected between 2009 and 2020...

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PMID: 35437792
DOI: 10.1002/mds.29027

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