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Article

Comprehensive cross-sectional and longitudinal analyses of plasma neurofilament light across FTD spectrum disorders

1 Apr 2022

Abstract excerpt

Frontotemporal dementia (FTD) therapy development is hamstrung by a lack of susceptibility, diagnostic, and prognostic biomarkers. Blood neurofilament light (NfL) shows promise as a biomarker, but studies have largely focused only on core FTD syndromes, often grouping patients with different diagnoses. To expedite the clinical translation of NfL, we avail ARTFL LEFFTDS Longitudinal Frontotemporal Lobar...

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PMID: 35492244
DOI: 10.1016/j.xcrm.2022.100607

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