Article

Differential Requirements for the CENP-O Complex Reveal Parallel PLK1 Kinetochore Recruitment Pathways

2020-11-30

Abstract excerpt

Similar to other core biological processes, the vast majority of cell division components are essential for viability across human cell lines. However, genome-wide screens have identified a number of proteins that exhibit cell line-specific essentiality. Defining the behaviors of these proteins is critical to our understanding of complex biological processes. Here, we harness differential essentiality to reveal th...

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Literature Corpus work: 90dc0e87-4a27-5fe0-bbcd-2a3e6397f467
DOI: 10.1101/2020.11.30.404327

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