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Bloom syndrome helicase contributes to germ line development and longevity in zebrafish

2021-03-16

Abstract excerpt

RecQ helicases - also known as the ‘guardians of the genome’ - play crucial roles in genome integrity maintenance through their involvement in various DNA metabolic pathways. Aside from being conserved from bacteria to vertebrates, their importance is also reflected in the fact that in humans impaired function of multiple RecQ helicase orthologs are known to cause severe sets of problems, including Bloom, Werner o...

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Identifiers and source

Literature Corpus work
90d7fa19-2fe6-557e-9926-a4eb7e8551f1
DOI
10.1101/2021.03.16.435627
Open publication

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Bloom syndrome helicase contributes to germ line development and longevity in zebrafishDOI 10.1101/2021.03.16.435627
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