Article

The role of Fas signalling and the c-MYC oncogene in T cell apoptosis and transformation

2001-01-01

Abstract excerpt

Cancer is a disease characterised by disruption of apoptotic pathways and inappropriate expression of survival or proliferative signals. Despite its role as a major apoptotic pathway in T cells however, the role of Fas in lymphomagenesis is not clear. To investigate the role of Fas in MYC induced lymphomagenesis, animals harbouring a c-MYC transgene, with expression targeted to the T cell lineage, were placed on a...

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Literature Corpus work: 90a70823-bb66-56cb-b207-826186d71b79
DOI: 10.5525/gla.thesis.73169

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