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Article

FasL deficiency enhances the development of tumors in p53+/- mice.

Toxicologic pathology - 1 Jan 2000

Embree-Ku Michelle, Boekelheide Kim

Abstract excerpt

In the multistep process of tumor development, several events occur to transform cells from normal to malignant. Although p53 is one of the most commonly mutated genes in a wide variety of tumors, how other genes interact with p53 to transform cells is only just beginning to be understood. To study the effects of the interaction of the Fas system with p53 in tumor progression and development, mice with a targeted...

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Identifiers

PMID: 12512872
DOI: 10.1080/01926230290166797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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FasL deficiency enhances the development of tumors in p53+/- mice.PMID 12512872Read ↗

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