Cell death regulation during multistep lymphomagenesis.

doi:10.1016/0304-3835(95)03836-l

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Article

Cell death regulation during multistep lymphomagenesis.

Cancer letters - 20 Jul 1995

Hsu B, Marin M C, McDonnell T J

Abstract excerpt

The three most common genetic abnormalities occurring in malignant lymphomas involve alterations resulting in the deregulated expression of the c-myc and bcl-2 oncogenes and the inactivation of the p53 tumor suppressor gene. Relevant strains of genetically engineered mice, including bcl-2-Ig and...

Topics

Animals
Apoptosis
Cell Division
Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 18
Chromosomes, Human, Pair 8
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor
Genes, myc
Genes, p53
Humans
Lymphoma
Mice
Mice, Transgenic
Mutation
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-bcl-2
Proto-Oncogene Proteins c-myc

Source

Open in PubMed

Identifiers

PMID: 7621440
DOI: 10.1016/0304-3835(95)03836-l

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7621440-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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