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Article

p53-dependent impairment of T-cell proliferation in FADD dominant-negative transgenic mice.

Current biology : CB - 9 Apr 1998

Zörnig M, Hueber A O, Evan G

Abstract excerpt

Members of the tumour necrosis factor (TNF) receptor family exert pleiotropic effects and can trigger both apoptosis and proliferation [1]. In their cytoplasmic region, some of these receptors share a conserved sequence motif - the 'death domain' - which is required for transduction of the apoptotic signal by recruiting other death-domain-containing adaptor molecules like the Fas-associated protein FADD/MORT1 or...

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Source

Identifiers

PMID: 9550704
DOI: 10.1016/s0960-9822(98)70182-4

Genes

FADD
TNF
TRADD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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p53-dependent impairment of T-cell proliferation in FADD dominant-negative transgenic mice.PMID 9550704Read ↗

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