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Modeling Atrial Fibrillation through Intermittent Tachypacing-Induced Remodeling in hiPSC-Derived Atrial Cardiomyocytes and Atrial Fibroblast

2025-05-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Human in vitro models for atrial fibrillation (AF) are limited. Human-induced pluripotent stem cell-derived atrial cardiomyocytes (hiPSC-aCMs) provide a valuable tool to study AF pathophysiology by facilitating in vitro modeling. <h4>Objectives</h4> To investigate the effects of an intermittent tachypacing protocol (ITPP) in matured hiPSC-aCMs co-cultured with human atri...

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Literature Corpus work
90955b4d-9c32-5460-8e2f-5e0098e2bf26
DOI
10.1101/2025.05.23.655123
Open publication

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Modeling Atrial Fibrillation through Intermittent Tachypacing-Induced Remodeling in hiPSC-Derived Atrial Cardiomyocytes and Atrial FibroblastDOI 10.1101/2025.05.23.655123
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