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Article

Rat atrial engineered heart tissue: a new in vitro model to study atrial biology.

Basic research in cardiology - 3 Sept 2018

Krause Julia, Löser Alexandra, Lemoine Marc D, Christ Torsten, Scherschel Katharina, Meyer Christian, Blankenberg Stefan, Zeller Tanja, Eschenhagen Thomas, Stenzig Justus

Abstract excerpt

Engineered heart tissue (EHT) from rat cells is a useful tool to study ventricular biology and cardiac drug safety. Since atrial and ventricular cells differ significantly, EHT and other 3D cell culture formats generated from ventricular cells have been of limited value to study atrial biology. To date, reliable in vitro models that reflect atrial physiology are lacking. Therefore, we established a novel EHT...

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PMID: 30178427
DOI: 10.1007/s00395-018-0701-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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