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Article

Immune response caused by M1 macrophages elicits atrial fibrillation-like phenotypes in coculture model with isogenic hiPSC-derived cardiomyocytes.

Stem cell research & therapy - 4 Sept 2024

Hutschalik Thomas, Özgül Ozan, Casini Marilù, Szabó Brigitta, Peyronnet Rémi, Bártulos Óscar, Argenziano Mariana, Schotten Ulrich, Matsa Elena

Abstract excerpt

BACKGROUND: Atrial fibrillation has an estimated prevalence of 1.5-2%, making it the most common cardiac arrhythmia. The processes that cause and sustain the disease are still not completely understood. An association between atrial fibrillation and systemic, as well as local, inflammatory processes has been reported. However, the exact mechanisms underlying this association have not been established. While it is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39227896
DOI: 10.1186/s13287-024-03814-0
PMCID: PMC11373469

Genes

ATP1A1
GJA5
KCNA5
SCN5A

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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