Article

Drug Screening Platform Using Human Induced Pluripotent Stem Cell-Derived Atrial Cardiomyocytes and Optical Mapping

2020-07-15

Abstract excerpt

<h4> A bstract </h4> Current drug development efforts for the treatment of atrial fibrillation (AF) are hampered by the fact that many preclinical models have been unsuccessful in reproducing human cardiac atrial physiology and its response to medications. In this study, we demonstrated an approach using human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes (hiPSC-aCMs and hiPSC-vCMs...

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Literature Corpus work: d9c09257-b6b0-5c8e-b50e-b8a4487f3b0d
DOI: 10.1101/2020.07.14.203232

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