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Human Engineered Heart Tissue Models for Pharmacological Studies-Inhibition of Small-Conductance Ca <sup>2+</sup> -activated K <sup>+</sup> (K <sub>Ca</sub> 2) channel

2025-10-02

Abstract excerpt

<h4>ABSTRACT</h4> Atrial fibrillation (AF) is a common cardiac arrhythmia increasing stroke risk. Current treatments show limited effectiveness and can cause serious side effects. At the moment there is a lack of well-established human models recapitulating complex cardiac microenvironment for studying potential AF therapies. To address the limitations of existing models we developed 3D in vitro human Engineered...

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Literature Corpus work
fee2ddd4-2c0f-51b6-96b7-524d64458db9
DOI
10.1101/2025.09.30.679523
Open publication

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Human Engineered Heart Tissue Models for Pharmacological Studies-Inhibition of Small-Conductance Ca <sup>2+</sup> -activated K <sup>+</sup> (K <sub>Ca</sub> 2) channelDOI 10.1101/2025.09.30.679523
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